Hormone-dependent cancers: molecular mechanisms and therapeutical implications

G Emons - Cells, 2022 - mdpi.com
… and progression of these hormone-dependent malignancies. … important aspects of the
current knowledge of hormone … or acquired resistance of breast cancer to endocrine therapy. In …

Molecular mechanisms of hormone resistance of breast cancer

AM Scherbakov, MA Krasil'Nikov… - Bulletin of experimental …, 2013 - Springer
Progress in understanding of BC hormone resistance … /Akt pathway to ER, is also described
for hormone-dependent BC cells: PI3K and Akt cause ER activation [… Modern concepts on the …

Hormonal impact on tumor growth and progression

A Reznikov - Experimental oncology, 2015 - dspace.nbuv.gov.ua
cancer growth and transition to hormone therapy resistant … , growth and progress of
hormone-dependent tumors. Further … mechanisms of hormonal impact on tumor growth and …

Hormone-dependent cancers: new aspects on biochemistry and molecular pathology

Y Miki - International Journal of Molecular Sciences, 2023 - mdpi.com
… of the mechanisms of hormone action have been identified as … However, several patients
show resistance to these hormone … In recent years, androgen action in breast and endometrial …

Endocrine resistance in hormone receptor positive breast cancer–from mechanism to therapy

A Rani, J Stebbing, G Giamas, J Murphy - Frontiers in endocrinology, 2019 - frontiersin.org
… In this review, we summarize current progress in our understanding of ER biology and the
molecular mechanisms that predispose and determine endocrine resistance in breast cancer

Therapeutic advances in hormone-dependent cancers: focus on prostate, breast and ovarian cancers

M Ulm, AV Ramesh, KM McNamara… - Endocrine …, 2019 - ec.bioscientifica.com
… the current therapeutic trends in hormonal cancers, with … therapy, but once PCa becomes
resistant to any treatment, it … help the progression of CRPC, and mechanisms accounting for the …

[КНИГА][B] Drug and Hormone Resistance in Neoplasia

N Bruchovsky, JH Goldie - 1983 - api.taylorfrancis.com
… mutations to drug resistance as an important mechanism, as … manifestations of a
hormone-dependent tumor. While nursing … disease progression must be evident prior to therapy. …

Pioneer factors in hormone-dependent cancers

KM Jozwik, JS Carroll - Nature Reviews Cancer, 2012 - nature.com
mechanisms contribute to resistance in hormone-dependent … patients who have acquired
resistance to current treatments. … have a role in hormone-dependent cancer progression, it is of …

Models and mechanisms of acquired antihormone resistance in breast cancer: significant clinical progress despite limitations

EE Sweeney, RE McDaniel, PY Maximov… - … molecular biology and …, 2012 - degruyter.com
… disappointing clinically until the recent successful use of … our understanding of
hormone-dependent cancer growth [32] … tumor growth: a unifying concept in anti-hormone …

Steroidhormone receptors as targets for the therapy of breast and prostate cancerrecent advances, mechanisms of resistance, and new approaches

J Hoffmann, A Sommer - The Journal of steroid biochemistry and molecular …, 2005 - Elsevier
… nuclear receptors led to the concept that inhibition of steroid … tumour progression in
tamoxifen-resistant breast cancer models. … tumour growth inhibition in a panel of hormone-dependent