Modelling hepatitis C therapy—predicting effects of treatment
AS Perelson, J Guedj - Nature reviews Gastroenterology & hepatology, 2015 - nature.com
… We searched PubMed for English-language articles that focused on hepatitis C viral
kinetics, estimating effectiveness of therapy and determining the duration of therapy using the …
kinetics, estimating effectiveness of therapy and determining the duration of therapy using the …
Modeling the dynamics of Hepatitis C virus with combined antiviral drug therapy: Interferon and Ribavirin
… A mathematical modeling of hepatitis C virus (HCV) dynamics and antiviral therapy has … the
addition of ribavirin to interferon therapy and explains the dynamics regarding a biphasic and …
addition of ribavirin to interferon therapy and explains the dynamics regarding a biphasic and …
Hepatitis C viral dynamics using a combination therapy of interferon, ribavirin, and telaprevir: mathematical modeling and model validation
P Aston, K Cranfield, H O'Farrell… - Hepatitis C-From …, 2018 - books.google.com
… treatment of chronic Hepatitis C virus infection. We introduce a mathematical model for Hepatitis
C dynamics treated … and ribavirin treatments to understand how this combination therapy …
C dynamics treated … and ribavirin treatments to understand how this combination therapy …
Modeling hepatitis C virus dynamics: Liver regeneration and critical drug efficacy
… viral (HCV) RNA kinetics have provided a means of evaluating the antiviral effectiveness of
therapy… Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy. …
therapy… Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy. …
Dynamics of hepatitis C under optimal therapy and sampling based analysis
G Pachpute, SP Chakrabarty - … Nonlinear Science and Numerical Simulation, 2013 - Elsevier
… We examine two models for hepatitis C viral (HCV) dynamics, one for monotherapy with …
the other for combination therapy with IFN and ribavirin. Optimal therapy for both the models is …
the other for combination therapy with IFN and ribavirin. Optimal therapy for both the models is …
Mathematical analysis of multiscale models for hepatitis C virus dynamics under therapy with direct-acting antiviral agents
L Rong, AS Perelson - Mathematical biosciences, 2013 - Elsevier
… We study hepatitis C virus dynamics using a multiscale age-structured model. … Hepatitis C
virus (HCV) infection is a major cause of chronic liver disease, liver cirrhosis and liver cancer. …
virus (HCV) infection is a major cause of chronic liver disease, liver cirrhosis and liver cancer. …
Multiscale model of hepatitis C virus dynamics in plasma and liver following combination therapy
X Woot de Trixhe, W Krzyzanski… - CPT …, 2021 - Wiley Online Library
… models capture the evolution of the entire (infected) cell population to derive the overall
dynamics … In this article, we apply the PSP model for the first time to describe the dynamics of …
dynamics … In this article, we apply the PSP model for the first time to describe the dynamics of …
[HTML][HTML] Dynamic modeling of hepatitis C transmission among people who inject drugs
T Stocks, LJ Martin, S Kühlmann-Berenzon, T Britton - Epidemics, 2020 - Elsevier
… To support monitoring of progress toward viral hepatitis elimination, we developed and
implemented a dynamic transmission model for hepatitis C (HCV) among people who inject …
implemented a dynamic transmission model for hepatitis C (HCV) among people who inject …
[HTML][HTML] Analysis of hepatitis C virus decline during treatment with the protease inhibitor danoprevir using a multiscale model
… and estimate its treatment effectiveness. The … virus dynamics in hepatitis C patients treated
with other DAAs currently in clinical development, and may help one to optimally combine …
with other DAAs currently in clinical development, and may help one to optimally combine …
[HTML][HTML] Scaling up prevention and treatment towards the elimination of hepatitis C: a global mathematical model
… We developed a dynamic transmission model of the global HCV epidemic, calibrated to 190
… drugs (PWID), current coverage of treatment and prevention programmes, natural history of …
… drugs (PWID), current coverage of treatment and prevention programmes, natural history of …