… We searched PubMed for English-language articles that focused on hepatitis C viral
kinetics, estimating effectiveness of therapy and determining the duration of therapy using the …

… A mathematical modeling of hepatitis C virus (HCV) dynamics and antiviral therapy has … the
addition of ribavirin to interferon therapy and explains the dynamics regarding a biphasic and …

… Here, we describe a viral dynamic model of response to TPR treatment. The model
incorporates the presence of viral variants of differing degrees of resistance and fitness, and the …

… Modelling early viral hepatitis C kinetics in compensated cirrhotic treatment-experienced
patients treated with triple therapy including telaprevir or … Laouénan C, Guedj J, Mentré F. …

… We study hepatitis C virus dynamics using a multiscale age-structured model. … Hepatitis C
virus (HCV) infection is a major cause of chronic liver disease, liver cirrhosis and liver cancer. …

… In conclusion, mathematical modeling together with experimental data has provided a rich
… toward finding a cure for hepatitis B following the success of hepatitis C treatment, great …

… novel approach to modeling the viral kinetics in hepatitis C. First, a nonlinear mixed-effects …
CHC who received treatment with peginterferon α-2a, alone or in combination with ribavirin, …

… and estimate its treatment effectiveness. The … virus dynamics in hepatitis C patients treated
with other DAAs currently in clinical development, and may help one to optimally combine …

… Simple models of therapy for viral diseases such as hepatitis C virus (HCV) or human …
that, once therapy is started, the drug has a constant effectiveness. More realistic models have …

… (SA) and medically assisted treatment (MAT) have shown mixed results in lowering HCV …
cumulative effects of combining DAA and MAT treatment. While simulation experiments can …