CARBOHYDRATES MALABSORPTION IN CLINICAL PRACTICE OF PEDIATRICS

Authors

DOI:

https://doi.org/10.30888/2663-5712.2025-29-01-007

Keywords:

Сhildren, lactose intolerance, fructose intolerance, sorbitol malabsorption, hydrogen breath tests, carbohydrates malabsorption

Abstract

Food intolerance is one of the problems that pediatricians most often face in their practice. The main place in the structure of this pathology is occupied by malabsorption of carbohydrates - a group of diseases caused by impaired breakdown and / or abso

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References

Nwaru BI, Hickstein L., Panesar SS et al. Anaphylaxis Guidelines G. Prevalence of common food allergies in Europe: a systematic review and meta-analysis. Allergy. 2014; 69: 992 – 1007. Doi: 10.1111/all.12423.

Hon E, Gupta SK. Gastrointestinal food allergies and intolerances. Gastroenterol Clin North Am 2021; 50:41 – 57. Doi: 10.1016/j.gtc.2020.10.006

Fernando Fernandez-Banares. Carbohydrate maldigestion and intolerance. Nutrients. 2022; 14 (9): 1923. Doi: 10.3390/nu14091923.

Sumit Kumar Singh, Moinak Sen Sarma. Hereditary fructose intolerance: a comprehensive review. World J. Clin Pediatr. 2022; 11 (4): 321 – 329. Doi: 10.5409/wjcp.v11.i4.321.

Hammer HF, et al. Diarrhea caused by carbohydrate malabsorption. Gastroenterol Clin North Am. 2012; 41(3): 611-27. Doi: 10.1016/j.gtc.2012.06.003.

Matthew Burke. Carbohydrate intolerance and disaccharides measurement – a mini-review. Clin. Biochem. Rev. 2019; 40(4): 167 – 174. DOI: 10.33176/AACB-19-00025.

Cohen SA, Oloyede H, Gold BD, Mohammed A, Elser HE. Clinical characteristics of disaccharidase deficiencies among children undergoing upper endoscopy. J Pediatr Gastroenterol Nutr. 2018;66(suppl 3):S56–S60. doi: 10.1097/MPG.0000000000001961.

Rezaie A, Buresi M, Lembo A. Hydrogen and methane-based breath testing in gastrointestinal disorders: the north American consensus. Am J Gastroenterol. 2017;112:775–784. doi: 10.1038/ajg.2017.46.

Misselwitz B, Butter M, Verbeke K, et al. Update on lactose malabsorption and intolerance: pathogenesis, diagnosis and clinical management. Gut. 2019;68(11):2080–2091. doi:10.1136/gutjnl-2019-318404.

Chumpitazi BP, et al. Demographic and clinical correlates of mucosal disaccharidase deficiencies in children with functional dyspepsia. J Pediatr Gastroenterol Nutr. 2018;66(Suppl 3):52–55.

El-Chammas K, Williams SE, Miranda A. Disaccharidase deficiencies in children with chronic abdominal pain. JPEN J Parenter Enteral Nutr. 2017;41(3):463–469. doi:10.1177/0148607115594675.

Wasuwanich P, Choudry H, Ingviya T, et al. A retrospective study on the association of gastrointestinal symptoms in children with low lactase activity and low activity of other disaccharidases. BMC Gastroenterol. 2020;20(1):331. doi:10.1186/s12876-020-01443-4.

Hanna Fjeldheim Dale et al. Disaccharidase deficiencies and gastrointestinal symptoms in patients referred to gastroscopic examination: a single center study from Norway. Scand J Gastroenterol. 2024; 59(10): 1166 – 1171. doi:10.1080/00365521.2024.2395848.

M. Raithel et al. The malabsorption of commonly occuring mono and disaccharides: levels of investigation and differential diagnoses. Dtsch Arztebl Int. 2013. 2013 Nov 15;110(46):775-82. doi: 10.3238/arztebl.2013.0775.

D. Bushyhead, E.M.M. Quigley. Small intestinal bacterial overgrowth – pathophysiology and its implications for definition and management. Gastroenterology 2022;163:593–607. doi.org/10.3390/biomedicines12051030.

M. del Carmen Toca, A. Fernandez, M. Orsi et al. Lacose intolerance: myths and facts. An update. Arch Argent Pediatr 2022;120(1):59-66. doi.org/10.5546/aap.2022.eng.59

Montoro-Huguet MA, Belloc B, Domínguez-Cajal M. Small and large intestine: malabsorption of nutrients. Nutrients. 2021 Apr 11;13(4):1254. doi: 10.3390/nu13041254.

Catanzaro, R., Sciuto, M. & Marotta, F. Lactose Intolerance—Old and New Knowledge on Pathophysiological Mechanisms, Diagnosis, and Treatment. SN Compr. Clin. Med. 3, 499–509 (2021). doi.org/10.1007/s42399-021-00792-9.

Ugidos-Rodríguez S, Matallana-González MC, Sánchez-Mata MC. Lactose malabsorption and intolerance: a review. Food Funct. 2018;9:4056–68. DOI: doi.org/ 10.1039/c8fo00555a

Gasbarrini A, Corazza GR, Gasbarrini G, Montalto M, Di Stefano M, Basilisco G, et al. Methodology and indications of H2-breath testing in gastrointestinal diseases: the Rome Consensus Conference. Aliment Pharmacol Ther. 2009;29:1–49. doi.org/10.1111/j.1365-2036.2009.03951.x.

Singh SK, Sarma MS. Hereditary fructose intolerance: A comprehensive review. World J Clin Pediatr 2022; 11(4): 321-329. DOI: 10.5409/wjcp.v11.i4.321]

Twain Sia, Riki O. Tanaka, Albert Mousad et al. Fructose malabsorption and fructan malabsorption are associated in patients with irritable bowel syndrome. BMC Gastroenterology. 2024 Apr 24;24(1):143.doi: 10.1186/s12876-024-03230-x.

Ebert K, Witt H. Fructose malabsorption. Mol Cell Pediatr. 2016;3(1):10. doi: 10.1186/s40348-016-0035-9.

F. Fernandez-Banares, M. Esteve, J.M. Viver. Fructose-sorbitol malabsorption. Curr Gastroenterol Rep. 2009; 11(5):368-74. doi: 10.1007/s11894-009-0056-9.

Helwig U, Koch AK, Koppka N, Holtmann S, Langhorst J: The predictive value of the hydrogen breath test in the diagnosis of fructose malabsorption. Digestion 2019, DOI: 101159/0000489877.

B. Klee, O. Barske, A. Mack et al. Sorbitol malabsorption in patients with abdominal discomfort. Minerva Gastroenterologica e Dietologica 2018; 64(2): 117-23. doi.org/10.23736/S1121-421X.17.02329-7.

Gatia Granja. Recurrent abdominal pain caused by sorbitol malabsorption. Glob J of Ped & Neonatol Car. 2021; 3(3). GJPNC. MC. ID.000564.

M. Moltalto, A. Gallo, V. Ojetti et al. Fructose, trehalose and sorbitol malabsorrption. European review for medical and pharmacological sciences. 2013; 17(2): 26 – 29. PMID: 24443064.

Published

2025-01-30

How to Cite

Горобець, А., & Прощенко, Ю. (2025). CARBOHYDRATES MALABSORPTION IN CLINICAL PRACTICE OF PEDIATRICS. SWorldJournal, 1(29-01), 120–133. https://doi.org/10.30888/2663-5712.2025-29-01-007

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