SCIENTIFIC RESEARCH ON TOPICAL ANESTHESIA IN PERMANENT MAKEUP: RISK ASSESSMENT AND PRESENTATION OF A NEW METHOD

Authors

DOI:

https://doi.org/10.30888/2663-5712.2025-34-05-132

Keywords:

topical anesthesia, topical anesthetics, chemical burns, allergic reactions, dermatological safety, permanent makeup, standardization of protocols.

Abstract

The paper addresses the current issue of comprehensively assessing the safety and effectiveness of anesthesia application methods. Topical anesthesia is a crucial stage in the permanent makeup procedure, as it determines the level of patient comfort, the

References

Islam RK, Tong VT, Robicheaux C., Tageant H., Haas CJ, Kline RJ, Islam KN the Impact of Anesthesia on Dermatology Outcomes: A Narrative Review // Cureus. 2024. Vol. 16(10). P. e72321. DOI: 10.7759/cureus.72321

Dziabas DC, Kasai MMS, Lobo MA, Esclavacini MV, Chicone G. All-in-One Protocol: A Comprehensive Sedation Approach for Multi-Procedural Aesthetic Dermatology // J Cosmet Dermatol. 2025. Vol. 24(8). P. e70400. DOI: 10.1111/jocd.70400.

Ghafari G., Newcomer J., Rigali S., Liszewski W. Permanent makeup: A review of its technique, regulation, and complications // Journal of the American Academy of Dermatology. 2024. Vol. 91(4). P. 690–698. DOI: 10.1016/j.jaad.2024.01.098.

Jiang S., Tang M. Allergy this Local Anesthetics is a Rarity: Review of Diagnostics and Strategies for Clinical Management // Clin Rev. Allergy Immunol. 2023. Vol. 64(2). - P. 193-205. DOI: 10.1007/s12016-022-08937-x.

Sanchez MF, Breda SA, Soria EA, Tártara LI, Manzo RH, Olivera ME Ciprofloxacin-lidocaine-based hydrogel: development, characterization, and in live evaluation in a second degree burn model // Drug delivery and translational research. 2018. Vol. 8(5). P. 1000–1013. DOI: 10.1007/s13346-018-0523-7

Cook KA, Kelso JM Surgery-Related Contact Dermatitis: A Review of Potential Irritants and Allergens // The journal of allergy and clinical immunology. In practice. 2017. Vol. 5(5). P. 1234–1240. DOI: 10.1016/j.jaip.2017.03.001

Seo MK, Yoo GJ, Bae HM, Lee JH, Kim HS, Kim HK Detection of Local Anesthetic Ingredients Including Lidocaine, Tetracaine, and Prilocaine in Illegally Distributed Drugs Through Gas Chromatography-Time-of-Flight Mass Spectrometry and Gas Chromatography-Triple Quadrupole Mass Spectrometry. Journal of mass spectrometry // JMS. 2025. Vol. 60(12). P. e5189. DOI: 10.1002/jms.5189

de Groot A. Allergic Contact Dermatitis from Topical Drugs: An Overview // Dermatitis: contact, atopic, occupational, drug. 2021. Vol. 32(4) - R. 197–213. DOI: 10.1097/DER.0000000000000737

Chamoun G., Forsyth A., Kazemeini S., Ma J., Lam K., Kasiri N., Frasier KM Systemic Risks of Topical Anesthetics in Barrier-Compromised Dermatologic Patients // Cureus. 2025. Vol. 17(5). P. e84157. DOI: 10.7759/cureus.84157

Sauce R., Pinto Caso, Velasco MVR, Rosado C., Baby AR Ex vivo penetration analysis and anti-inflammatory efficacy of the association of ferulic acid and UV filters // Eur J Pharm Sci. 2021. Vol. 156. P. 105578. DOI: 10.1016/j.ejps.2020.105578

Van Wicklin SA Local Anesthetic Systemic Toxicity // Plastic and aesthetic nursing. 2025. Vol. 45(4). P. 195–199. DOI: 10.1097/PSN.0000000000000674

Pióro W., Antoszewski B., Kasielska-Trojan A. Permanent Makeup Removal Severe Complication-Case Report and Proposal of the Protocol for Its Management // Journal of clinical medicine. 2024. Vol. 13(18). P. 5613. DOI: 10.3390/jcm13185613

Hamdan Al., Sataloff RT, Hawkshaw MJ Topical Anesthesia in Office-Based Laryngeal Surgery. In: Office-Based Laryngeal Surgery. Springer, Cham. 2022. DOI: 10.1007/978-3-030-91936-8

Khvashchak Y. Introducing the innovative Silk Touch technique into the training of permanent makeup artists // Pedagogical Academy: scientific notes. 2025. Vol. 19. DOI: 10.5281/zenodo.17060205

Chamoun G., Forsyth A., Kazemeini S., Ma J., Lam K., Kasiri N., Frasier KM Systemic Risks of Topical Anesthetics in Barrier-Compromised Dermatologic Patients // Cureus. 2025. Vol. 17(5). P. e84157. DOI: 10.7759/cureus.84157

Sun M., Osipitan OO, Sulicz EK, Di Pasqua AJ Preparation and Optimization of an Ultraflexible Liposomal Gel for Lidocaine Transdermal Delivery // Materials. 2022. Vol. 15(14). P. 4895. DOI: 10.3390/ma15144895

Shih BF, Huang FY, Shen SJ, Zheng CW, Lee CW, Yang MW, Chou AH, Chuang SS, Tsai HI an alternative to opioid-based intravenous patient controlled analgesia in severe burn patients undergoing full thickness split graft in upper limbs // J Plast Surg Hand Surg. - 2023. - Vol. 58. DOI: 10.2340/jphs.v58.12292

Liu Y., Zhang J., Yu P., Niu J., Yu S. Mechanisms and Efficacy of Intravenous Lipid Emulsion Treatment for Systemic Toxicity from Local Anesthetics // Frontiers in medicine. 2021. Vol. 8. P. 756866. DOI: 10.3389/fmed.2021.756866

Billowria K., Sandhu NK, Singh B. Topical Advances in Mucoadhesive Ocular Drug Delivery System // Current drug delivery. 2023. Vol. 20(8). P. 1127–1140. DOI: 10.2174/1567201819666221010122413

Farinha IC, Tavares FC, Faria E., Todo-Bom A., Coutinho IA Contact dermatitis to cinchocaine: is cross-reactivity between local anesthetics a problem? // Arq Asma Allerg Imunol. 2024. Vol. 8(2). P. 169-2. DOI: 10.5935/2526-5393.20230092

Meesters AA, Nieboer MJ, de Rie MA, Wolkerstorfer A. Parameters in fractional laser assisted delivery of topical anesthetics: A randomized controlled study on the role of the anesthetic and application time // J Am Acad Dermatol. 2019. Vol. 80(4). P. 1132-1133. DOI: 10.1016/j.jaad.2018.08.013

Cancio LC Topical Antimicrobial Agents for Burn Wound Care: History and Current Status // Surgical infections. 2021. Vol. 22(1). P. 3–11. DOI: 10.1089/sur.2020.368

Published

2025-11-30

How to Cite

Хвачак, Ю. (2025). SCIENTIFIC RESEARCH ON TOPICAL ANESTHESIA IN PERMANENT MAKEUP: RISK ASSESSMENT AND PRESENTATION OF A NEW METHOD. SWorldJournal, 5(34-05), 200–212. https://doi.org/10.30888/2663-5712.2025-34-05-132

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Articles